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Comprehensive analysis of the Twitter user experience in the iTunes App Store showed very plainly that people were looking for an app from Twitter—we didn't have one so they generally got confused and gave up. Obviously, we saw room for improvement.

Blog: Twitter for iPhone

http://blog.twitter.com/2010/05/twitter-for-iphone.html
http://www.nimbuzz.com/en/ "Nimbuzz is a great choice. Overall, the interfaces are clean, responsive and well-designed and the app in general has a slick, professional feel.

Nimbuzz - Free international mobile call chat messaging with sky

Neighbors offers a new dimension of communication in IM+ by providing users the opportunity to find new real life connections and friends with common interests. All your friends from all platforms are integrated into a single buddy list, and you can access multiple accounts simulatenously. Chat with friends on various platforms at the same time, in the same window - no switching or pre-registration required! http://www.shapeservices.com/en/products/details.php?product=im&platform=iphone

IM+ All-in-One Mobile Messenger: AIM/iChat, MSN/Windows Live Mes

Mobile Colloquy: Stay Connected

http://colloquy.mobi/ Colloquy for iPhone®, iPad™ and iPod® touch puts the power of the most popular IRC client for the Mac in the palm of your hand. Built atop the Chat Core framework, Colloquy Mobile is a full featured client optimized for the on-the-go experience.