Tricyclic Antidepressants - The Good, The Bad and The Funny. Fro. ‹ SNRIs | Antidepressant Topic Index | MAOIs › 1.
Three Ring Circus Defined by their three-ring chemical structure, almost all tricyclic antidepressants (TCAs) work in pretty much the same way: norepinephrine reuptake inhibition, alpha-1, H1, and M1 antagonism, and sodium voltage channel blocking. Most also do enough serotonin reuptake inhibition to make a difference, and some are also 5HT2A and 5HT2C antagonists. TCAs discussed on this site include: amitriptylineAnafranil (clomimpramine) clomipramine desipramine dosulepin / dothiepin - Not available in the US doxepin Elavil (amitriptyline) imipramineimipramine pamoateNorpramin (desipramine) nortriptylinePamelor (nortriptyline) Surmontil (trimipramine) Tofranil (imipramine) Tofranil-PM (imipramine pamoate) trimipramine maleate Vivactil (protriptyline) 2.
Tetracyclic - having four rings - antidepressants like Remeron and amoxapine are usually lumped in with TCAs even they don’t really work enough like TCAs to warrant that. 3. Onset of action of escitalopram compared with othe... [Int Clin. Triple reuptake inhibitors: a premise and promise. [Psychiatry I. Prozac (fluoxetine) - The Crazy Meds run-down.
Other Forms: Prozac Weekly, Sarafem (for PMDD), oral solution (It’s minty fresh!
Really, it tastes like mint-flavored mouthwash2.) Class: Antidepressants, specifically a Serotonin-Selective Reuptake Inhibitor (SSRI) 1. FDA Approved Uses of Prozac (fluoxetine) Major Depression for adults. 2. Fibromyalgia Arthritis Chronic Fatigue Multiple Sclerosis Bipolar Depression Lupus Headaches Irritable Bowel Syndrome (IBS) Premature Ejaculation 3. 3.1 Pros Prozac’s long half-life makes the issue of med compliance a little less of a big deal - hence the approval for depressed teenagers - and SSRI discontinuation syndrome is rarely anything like it is with other SSRIs, if it happens at all. 3.2 Cons The sexual side effects and weight gain, if it happens, can be pretty bad. 4. 4.1 Typical Side Effects of Prozac (fluoxetine HCl) The usual for SSRIs - headache, nausea, dry mouth, sweating, sleepiness or insomnia, and diarrhea or constipation, weight gain, loss of libido. Monoamine oxidase inhibitor.
Monoamine oxidase inhibitors (MAOIs) are chemicals which inhibit the activity of the monoamine oxidase enzyme family.
They have a long history of use as medications prescribed for the treatment of depression. They are particularly effective in treating atypical depression. They are also used in the treatment of Parkinson's Disease and several other disorders. Indications Newer MAOIs such as selegiline (typically used in the treatment of Parkinson's disease) and the reversible MAOI moclobemide provide a safer alternative and are now sometimes used as first-line therapy. MAOIs can also be used in the treatment of Parkinson's disease by targeting MAO-B in particular (therefore affecting dopaminergic neurons), as well as providing an alternative for migraine prophylaxis. Mechanism of action MAOIs act by inhibiting the activity of monoamine oxidase, thus preventing the breakdown of monoamine neurotransmitters and thereby increasing their availability.
Escitalopram: superior to citalopram or a chiral c... [Psychothe. Multiple Reuptake Inhibitors - The Good, The Bad and The Funny. Page design and explanatory material by Jerod Poore, copyright © 2004 - 2014.
All rights reserved. Keep up with Crazymeds and and/or my slow descent into irreparable madness boring life. Pick your preferred social media target(s): Almost all of the material on this site is by Jerod Poore and is copyright © 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, and 2014 Jerod Poore. Except, of course, the PI sheets - those are the property of the drug companies who developed the drugs the sheets are about - and any documents that are written by other people which may be posted to this site will remain the property of the original authors. All rights reserved. ‘Everything is true, nothing is permitted.’ - Jerod Poore 1 While there are plenty of books to help you with hypochondria, for some reason there’s not much in the way of websites. 2 Remember kids, Microsloth operating systems are like TOS Star Trek movies with in that every other one sucks way, way more.