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Cell Viability Assays - Creative Bioarray. Cell Proliferation Assays - Creative Bioarray. With our professional scientists and an integrated technical platform, Creative Bioarray is able to provide the best customized cell proliferation assay services for worldwide customers.

Cell Proliferation Assays - Creative Bioarray

Cell Immortalization Services - Creative Bioarray. Creative Bioarray provides cell immortalization services based our experienced scientists and elaborate technical platforms.

Cell Immortalization Services - Creative Bioarray

We have successfully immortalized cells from multiple tissues and species. We have the ability to meet all your needs. Custom Cell Line Services - Creative Bioarray. As one of the world’s largest independent biotechnology companies, Creative Bioarray has a series of advanced technologies for stable cell line construction and rich experience in cell culture.

Custom Cell Line Services - Creative Bioarray

We can provide reliable custom cell line services of various cell types based on our proprietary expression vector, efficient gene screening and amplification system, high throughput cell screening technologies and comprehensive development capabilities. We have successfully developed a variety of customized cell lines for our customers all over the world, including but not limited to gene overexpression cell lines, gene knockdown cell lines, gene knockout cell lines, gene modification cell lines, and reporter cell lines. We offer high quality, fast turnaround and cost-effective stable cell lines to meet your specific needs of different applications, so as to help you in the research of gene function and expression regulation mechanism or assist you in new drug development. Figure 1. References: Custom Cell Culture Media Services - Creative Bioarray.

Creative Bioarray provides custom cell culture media services to meet the unique needs in cell culture applications, since catalog media do not always meet the requirements.

Custom Cell Culture Media Services - Creative Bioarray

We are committed to producing high quality cell culture media for biological research and pharmaceutical industry with fast turnaround time. No matter what kind of special medium you are looking for, we can provide made-to-order custom media according to your specific requirements. Almost any catalog media formulation can be customized. We can also help you evaluate and optimize the current cell media formulations in order to find just the right one for you. With our help, your ideas can be converted into reality. Cell Cryopreservation and Cell Banking Services - Creative Bioarray. Cell Co-Culture Services - Creative Bioarray. Creative Bioarray can provide cell co-culture services of various cell types according to customer's requirement.

Cell Co-Culture Services - Creative Bioarray

We have the ability to co-culture multiple cell types used for various applications, such as cancer study, drug discovery and development, tissue engineering, and developmental biology. Basic and Large-Scale Cell Culture Services - Creative Bioarray. Cell Culture is a routinely task for most laboratories and pharmaceutical companies.

Basic and Large-Scale Cell Culture Services - Creative Bioarray

It is close related to various applications, including scientific research, drug research and development, and biopharmaceutics. Cell culture is the premise of reliable scientific findings and stable production. However, cell culture can be affected by many factors, such as contamination, unstable culture conditions and different protocols. Cell Invasion Assays - Creative Bioarray. Creative Bioarray provides customized solutions based on different cell invasion assays according to different requirements to accelerate your fundamental research and drug development projects.

Cell Invasion Assays - Creative Bioarray

Introduction of Cell Invasion Cell invasion is a phenotypic characteristic related to cell migration. The difference is that cell invasion defines the ability of cells to migrate within a tissue or infiltrate into neighbouring tissues through the extracellular matrix, which is degraded by protease in the process of invaison. Cell invasion is involved in pathological processes of many diseases. Cell Migration Assays - Creative Bioarray. Creative Bioarray provides a wide selection of tailored cell migration assays and powerful analysis to accelerate your fundamental research and drug development projects.

Cell Migration Assays - Creative Bioarray

Introduction of Cell Migration Cell migration is a fundamental and essential biological process for the development and maintenance of multicellular organisms. It generally refers to the translation of cells from one location to another in response to specific external signals. Cell Adhesion Assays - Creative Bioarray. Creative Bioarray provides diverse cell adhesion assays and reliable results for fundamental research and drug development projects.

Cell Adhesion Assays - Creative Bioarray

With a scientific team with professional knowledge and strong practical skills, we can customize the best solution to meet the specific needs of our customers. Introduction of Cell Adhesion Cell adhesion is a complex process, involving multiple molecular interactions and a range of biological events. Clonogenic Assays - Creative Bioarray. Creative Bioarray has experienced scientific team and state-of-the-art platform to provide reliable clonogenic assays for our customers worldwide.

Clonogenic Assays - Creative Bioarray

We are your ideal partner in fundamental research and drug development. Introduction of Clonogenic Assays Clonogenic assay, also known as colony formation assay, is an in vitro cell survival assay, which evaluates all modalities of cell death according to the ability of a single cell to grow into a colony. The assay essentially determines every cell in the population for its ability to proliferate indefinitely. Cell Senescence Assays - Creative Bioarray. At Creative Bioarray, our professional scientific team can provide a wide selection of cellular senescence assays based on our advanced platform. We can assist your foundamental research and accelerate your drug development projects. Introduction of Cellular Senescence The life course of cells must go through several stages, including undifferentiated state, differentiation, growth, maturity, senescence and death.

Cellular senescence is one of the most fundamental cell behaviours, and is also considered to play a critical role in the regulation of cell life. The dynamic balance of cell senescence, cell death and the growth of new cells is the basis of maintaining the normal life activities of organisms. Cellular senescence is a highly coordianted and programmed cellular state comprising a highly stable and irreversible cell cycle arrest in response to stress or damage. Figure 1. Cellular senescence is a physiological phenomenon that has both beneficial and detrimental consequences. Autophagy Assays - Creative Bioarray.

With state-of-the-art platform and experienced scientific team, Creative Bioarray can provide a wide selection of autophagy assays to accelerate our customer's research and drug development project. Introduction of Autophagy Autophagy is a dynamic intracellular degration process. It allows the orderly autophagosomic-lysosomal degradation and recycling of unnecessary or dysfuncitonal cellular components, such as abnormal protein aggregates, bulk cytoplasmic contents, and excess or damaged organelles. Microautophagy, macroautophagy and chaperone-mediated autophagy (CMA) are three major forms. They can be activated by various exogenous and endogenous stimuli. Autophagy is a physiologically essential and highly regulated catabolic pathway. Abnormal autophagy is implicated in many pathological conditions.

Figure 1. Custom Cell Line Services - Creative Bioarray. Cell Cryopreservation and Cell Banking Services - Creative Bioarray. Fibroblast Cells And Media. Fibroblast is a type of cell that synthesizes extracellular matrix and collagen, which form the basic framework structure of biological connective tissue in animals and play an important role in tissue repair. As well as being present as fibroblasts, these cells exist in an alternative state, as fibrocytes. Fibroblast is the term used to describe these cells when they are in an activated state. Fibrocyte refers to a state in which cells are less active. The morphology of fibroblasts depends on their function and site of action. Fibroblasts extracted from a particular location can "remember" their original location and function when transplanted to another location in the body. Fibroblast in Cutaneous Wound Repair Under normal conditions, fibroblasts function to maintain tissue homeostasis by regulating the turnover of extracellular matrix (ECM).

Fibroblast in Cancer. Epithelial Cells And Media. Epithelial cells are arranged in tightly packed layers that line the surfaces and cavities of tissues and organs throughout the body. It covers rang skins, respiratory tracts( nasal cavity and lungs ), alimentary tracts(oral cavity, stomach, intestines ), urogenital tract (kidney, vesicae, uterus and epididymis ), from all anacrine glnads (pancreas, gallbladder, mammary gland, salivary glands, lacrimal gland, sweat gland and etc. ), even some immune system organ (like thymus gland ).

The principle function of epithelial cells is to provide a protective layer for the organ they enclose but also provide other biological functions including secretion, selective absorption, filtration, protection and detection of sensation. The dysfunction of epithelial cells leads to a variety of diseases, infections and tumors. Therefore, epithelial cells are used in multiple research areas such as physiology, immunology, cytobiology, development and reproductive biology, molecular biology. Species: Endothelial Cells And Media. Endothelial cells are cells that line the inner surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall. The endothelial cells serve as a permeable barrier to regulate the passage of substances between blood-stream and surrounding tissue.

In basic research, endothelial cells are critical in applications related to wound healing, angiogenesis, blood brain barrier (BBB), inflammatory processes, diabetes and other cardiovascular diseases. Cell Viability Assays. Tips to Distinguish Epithelial Cells and Endothelial Cells – Creative Bioarray. While mentioning about epithelial cells and endothelial cells, it is not very easy to distinguish them clearly. Here are some features of epithelial cells and endothelial cells that can be used for further understand about this two cells. Endothelial cells cover the inner surface of the blood vessel, while the epithelial cells cover the inner surface of the internal organs and the outer surface of the human body.

If a large number of epithelial cells was found in the urine, it indicates urinary tract infection. Keratinocytes: Introduction, Function, and Significance – Creative Bioarray. Introduction Due to its large proportion of comprising epidermis cells over 90%, Keratinocyte is often known for being the predominant cell type in the epidermis—one of three parts of the skin but the outermost layer (the rest parts are the dermis and the subcutis or hypodermis. See more about skin cells in next blog). They are also being referred as basal cells, or basal keratinocytes, because of their special location in basal layer of the epidermis. Actually, except the skin, keratinocytes also cover some oral mucosa (as well as esophagus, corneal, conjunctival, and genital epithelia). However, the morphology of each tissue and the behavior of the keratinocytes from these site are quite different.

How Much Do You Know about White Blood Cells? – Creative Bioarray. Once speaking of white blood cells, people usually regard them as the body guarder: Whenever a bacteria and other foreign invasion enters the body, the white blood cells will notice and race toward the scene of the crime. They will take measures to protect the body against both infectious disease and foreign invaders. Truly they are, but how exactly take actions and how much do you know about them, for instance, the human monocytes? Cell Types in Bones – Creative Bioarray. As we all know that the skeleton is a dynamic organ. The bone cells’ coordinated actions determine the shape and form of body. This post is used to express the cell types in bones. Senescence Associated β-galactosidase Assay - Creative Bioarray. Normal mammalian cells divide in a fixed number of population doublings and eventually enter an arrested state in which the cells are still alive, but do not proliferate in response to mitogens, and exhibit a characteristic expanded, flattened morphology.

Senescence associated β-galactosidase (SA-β-gal) is a widely used biochemical marker for assessing cellular senescence. 7-AAD/CFSE Cell-Mediated Cytotoxicity Assay - Creative Bioarray. Cell-mediated cytotoxicity is characterized by the recognition and destruction of target cells (tumor or intracellular pathogen infected cells) by effector cells such as cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. LDH Cytotoxicity Assay - Creative Bioarray. Proliferating Cell Nuclear Antigen (PCNA) Assay - Creative Bioarray.

Ki-67 Cell Proliferation Assay - Creative Bioarray. CFSE Cell Proliferation Assay - Creative Bioarray. Sulforhodamine B (SRB) Cell Cytotoxicity Assay - Creative Bioarray. EdU Cell Proliferation Assay - Creative Bioarray. BrdU Cell Proliferation Assay - Creative Bioarray. Double Staining Apoptosis Assay (Hoechst33342/PI) DNA Laddering Assay. TUNEL Apoptosis Assay (Chromogenic) JC-1 Mitochondrial Membrane Potential Assay. Annexin V Apoptosis Assay. Caspase Activity Assay. Trypan Blue Staining Assay. ATP Cell Viability Assay. Calcein AM Cell Viability Assay. Resazurin Cell Viability Assay. Colorimetric Cell Viability Assay. Diseased Primary Cells. Fibroblast Cells And Media. Epithelial Cells And Media. Endothelial Cells And Media.