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Epistemology

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Rethinking the scientific method. On September 18, 2007, a few dozen neuroscientists, psychiatrists, and drug-company executives gathered in a hotel conference room in Brussels to hear some startling news. It had to do with a class of drugs known as atypical or second-generation antipsychotics, which came on the market in the early nineties. The drugs, sold under brand names such as Abilify, Seroquel, and Zyprexa, had been tested on schizophrenics in several large clinical trials, all of which had demonstrated a dramatic decrease in the subjects’ psychiatric symptoms. As a result, second-generation antipsychotics had become one of the fastest-growing and most profitable pharmaceutical classes.

By 2001, Eli Lilly’s Zyprexa was generating more revenue than Prozac. It remains the company’s top-selling drug. But the data presented at the Brussels meeting made it clear that something strange was happening: the therapeutic power of the drugs appeared to be steadily waning. The study turned him into an academic star. The Unity of Science. First published Thu Aug 9, 2007; substantive revision Thu May 16, 2013 The topic of unity in the sciences includes the following questions: Is there one privileged, most basic kind of material, and if not, how are the different kinds of material in the universe related? Can the various natural sciences (physics, astronomy, chemistry, biology) be unified into a single overarching theory, and can theories within a single science (e.g., general relativity and quantum theory in physics) be unified?

Does the unification of these parts of science involve only matters of fact or are matters of value involved as well? What about matters of method, material, institutional, ethical and other aspects of intellectual cooperation? Moreover, what kinds of unity in the sciences are there, and is unification merely a relation between concepts or terms (i.e., a matter of semantics), or is it also a relation between the theories, people, objects, or objectives that they are part of?

1. Belief. First published Mon Aug 14, 2006; substantive revision Sun Nov 21, 2010 Contemporary analytic philosophers of mind generally use the term “belief” to refer to the attitude we have, roughly, whenever we take something to be the case or regard it as true. To believe something, in this sense, needn't involve actively reflecting on it: Of the vast number of things ordinary adults believe, only a few can be at the fore of the mind at any single time. Nor does the term “belief”, in standard philosophical usage, imply any uncertainty or any extended reflection about the matter in question (as it sometimes does in ordinary English usage). Many of the things we believe, in the relevant sense, are quite mundane: that we have heads, that it's the 21st century, that a coffee mug is on the desk. Forming beliefs is thus one of the most basic and important features of the mind, and the concept of belief plays a crucial role in both philosophy of mind and epistemology. 1. 1.1 Representationalism 1.1.1.