Amazon. What Can Alzheimer’s Disease Teach us About The Brain, Mind, And Self? - Rudolph Tanzi. Additional Benefit of Omega-3 Fatty Acids for the Clearance of Metabolites From the Brain – Neuroscience News. Summary: According to a new study, omega 3 polyunsaturates fatty acids can improve the function of the glymphatic system. Source: FASEB. Research in The FASEB Journal suggests that omega-3 polyunsaturated fatty acids could improve the function of the glymphatic system and promote clearance of amyloid-β peptides from the brain.
New research published online in The FASEB Journal suggests that omega-3 polyunsaturated fatty acids, which are found in fish oil, could improve the function of the glymphatic system, which facilitates the clearance of waste from the brain, and promote the clearance of metabolites including amyloid-β peptides, a primary culprit in Alzheimer’s disease. To make this discovery, scientists first used transgenic fat-1 mice, which express high endogenous omega-3 polyunsaturated fatty acids (PUFAs) in the brain, to investigate the effect of omega-3 PUFAs on the clearance function of the glymphatic system. About this neuroscience research article FASEB (2016, October 26). Probiotics improve cognition in Alzheimer's patients -- ScienceDaily.
For the first time, scientists have shown that probiotics -- beneficial live bacteria and yeasts taken as dietary supplements -- can improve cognitive function in humans. In a new clinical trial, scientists show that a daily dose of probiotic Lactobacillus and Bifidobacterium bacteria taken over a period of just 12 weeks is enough to yield a moderate but significant improvement in the score of elderly Alzheimer's patients on the Mini-Mental State Examination (MMSE) scale, a standard measure of cognitive impairment.
Probiotics are known to give partial protection against certain infectious diarrheas, irritable bowel syndrome, inflammatory bowel disease, eczema, allergies, colds, tooth decay, and periodontal disease. Here, the researchers, from Kashan University of Medical Sciences, Kashan, and Islamic Azad University, Tehran, Iran, present results from a randomized, double-blind, controlled clinical trial on a total of 52 women and men with Alzheimer's between 60 and 95 years of age. 'Mental Flossing' May Cut Cognitive Risk in Elderly. Action Points Engaging in mentally stimulating activities even in late life may be protective against new-onset mild cognitive impairment (MCI), according to a prospective observational study.Note that the associations of mentally stimulating activities with risk of MCI may vary according to carrier status of APOE ε4, a genotype that is a well-known risk factor for MCI and Alzheimer Disease.
Mentally stimulating activities may diminish the risk of mild cognitive impairment (MCI) in older people -- even in apolipoprotein E ε4 (APOE4) carriers, researchers found. In the population-based Mayo Clinic Study of Aging, several activities -- playing games, doing crafts, using the computer, and socializing -- were each associated with a significantly decreased risk of MCI in cognitively normal people age 70 and up over a median follow-up of 4 years, Yonas Geda, MD, of the Mayo Clinic in Scottsdale, Ariz., and colleagues reported online in JAMA Neurology. Reviewed by Henry A. 0xc128. The New Drug That Could Treat Alzheimer's - Introducing NTRX-07. In Brief Five million people, in the US alone, could be significantly helped by a new drug to treat Alzheimer's Disease. There have been many recent breakthroughs in the study and treatment of nuerodegenerative disorders. From medication to gene therapy, new solutions are continually popping up to instill greater hope.
Targeting Inflammation New developments and research into treating Alzheimer’s disease are always welcome. Researchers from the Department of General Anesthesiology at the Cleveland Clinic Lerner College of Medicine have developed a drug that promises an improved treatment. “This drug may reduce inflammation in the brain, which is linked to Alzheimer’s disease,” says lead researcher Mohamed Naguib of Cleveland Clinic. “NTRX-07 uses a different mechanism than many other Alzheimer’s drugs currently available, as it targets the cause of the disease, not just the symptoms,” Naguib explains. Restoring Memory and Lives. The pioneers | Spectrum. California became the first U.S. state to legalize medical marijuana, mainly for adults with severe chronic illness such as cancer or AIDS. Since California’s decision in 1996, 24 states and the District of Columbia (Washington, D.C.) have followed, and since 2012, four states and Washington, D.C., have legalized recreational use of the drug.
So far, only Pennsylvania specifically permits medical marijuana use for autism, but in the past few years, parents of children with epilepsy across the nation have adopted this approach. Much of this enthusiasm stemmed from the widespread media coverage in 2013 of Charlotte’s Web, a marijuana strain with high levels of CBD. The strain reportedly helped its namesake, Charlotte — a young girl with a form of epilepsy called Dravet syndrome — go from having hundreds of seizures a week to being practically seizure-free. Around that time, Karlee was at her wits’ end. Giving her son marijuana was not an easy decision for Karlee. Microarray Data :: Allen Brain Atlas: Human Brain. Role for Fatty Acid Metabolism in Preclinical AD? Action Points Note that this observational study found an association between higher levels of docosahexaenoic acid and lower levels of cerebral amyloidosis.Be aware that the study was focused on individuals with significant vascular risk factors and may not be generalizable to the population at large.
Limited seafood intake may increase the risk of brain amyloid deposition and Alzheimer's disease (AD), according to new research. Greater levels of the essential fatty acid docosahexaenoic (DHA) were associated with less cerebral amyloidosis, larger brain volumes, and better cognitive measures in cognitively healthy patients, Hussein N. Yassine, MD, of the University of Southern California, Los Angeles, and colleagues reported online in JAMA Neurology. In 61 older participants enrolled in the Aging Brain Study, serum DHA levels (the percentage of total fatty acids) were 23% lower in those with significantly more cerebral amyloidosis than in those without (0.97 versus 1.25).
Reviewed by F. Dietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brain. Sugar Harms Your Brain Health, Drives Alzheimer’s Epidemic. By Dr. Joseph Mercola Guest Writer for Wake Up World Alzheimer’s disease, a severe form of dementia, affects an estimated 5.2 million Americans, according to 2013 statistics. One in nine seniors over the age of 65 has Alzheimer’s, and the disease is now thought to be the third leading cause of death in the US, right behind heart disease and cancer.
A growing body of research suggests there’s a powerful connection between your diet and your risk of developing Alzheimer’s disease, via similar pathways that cause type 2 diabetes. Contrary to popular belief, your brain does not require glucose, and actually functions better burning alternative fuels, especially ketones, which your body makes in response to digesting healthy fats. According to some experts, such as Dr. Sugar Damages Brain Structure and Function In your brain, insulin helps with neuron glucose-uptake and the regulation of neurotransmitters, such as acetylcholine, which are crucial for memory and learning.
Neurologist Dr. Brain Science Institute (RIKEN BSI) This Is Your Brain on Drugs. The gray matter of the nucleus accumbens, the walnut-shaped pleasure center of the brain, was glowing like a flame, showing a notable increase in density. “It could mean that there’s some sort of drug learning taking place,” speculated Jodi Gilman, at her computer screen at the - Center for Addiction Medicine. Was the brain adapting to marijuana exposure, rewiring the reward system to demand the drug? Dr. Gilman was reviewing a composite scan of the brains of 20 pot smokers, ages 18 to 25. Moderate marijuana use by healthy adults seems to pose little risk, and there are potential medical benefits, including easing nausea and pain. Photo Marijuana samples seized by the federal Drug Enforcement Agency show the concentration of THC, the drug’s psychoactive compound, rising from a mean of 3.75 percent in 1995 to 13 percent in 2013.
High-THC marijuana is associated with paranoia and , according to a June article in The New England Journal of Medicine. A final test: Did Emma crave a joint? Study: Opioid Abuse Rates Lower In Medical Marijuana States. By Paul Armentano, NORML Deputy Director Rates of prescription opioid abuse are significantly lower in jurisdictions that permit medical marijuana access, according to data reported by Castlight Health, an employee health benefits platform provider.
Investigators assessed anonymous prescription reporting data from over one million employees between the years 2011 and 2015. In states that did not permit medical marijuana access, 5.4 percent of individuals with an opioid prescription qualified as abusers of the drug. (The study’s authors defined “abuse” as opioid use by an individual who was not receiving palliative care, who received greater than a 90-day cumulative supply of opioids, and received an opioid prescription from four or more providers.) By contrast, only 2.8 percent of individuals with an opioid prescription living in medical marijuana states met the criteria. Full text of the new study, “The opioid crisis in America’s workforce,” appears online here. TeenBrainandMj2012. Uncovering New Players in the Fight Against Alzheimer's. Peer inside the brain of someone with Alzheimer’s disease, and you’ll see some striking features: shriveled nerve cells and strange protein clumps.
According to a leading theory, proteins called amyloid beta and tau build up in the brain and choke nerve cell communication, setting the disease in motion years before people suspect anything is wrong with their recall. Yet the Alzheimer’s brain has another curious aspect. Some of the clusters of toxic amyloid proteins are entangled with octopus-like immune cells called microglia, cells that live in the brain to clear unwanted clutter. By munching on amyloid plaques, microglia are thought to help keep the disease at bay. For years scientists have probed how neuroinflammation contributes to Alzheimer’s disease and other neurodegenerative ailments. For decades multiple lines of evidence have given scientists a hunch that inflammation plays some role in Alzheimer’s.
Some researchers continue to believe inflammation plays a part, however. Efficacy of Souvenaid in mild Alzheimer's disease: results from a randomized, controlled trial. An implant to prevent Alzheimer's. In a cutting-edge treatment for Alzheimer's disease, EPFL scientists have developed an implantable capsule that can turn the patient's immune system against the disease. One of the hypothesized causes of Alzheimer's is the over-accumulation of the protein amyloid beta (Abeta) in different areas of the brain. This results in the deposition of aggregated protein plaques, which are toxic to neurons.
One of the most promising ways to fight the plaques is to "tag" the Abeta proteins with antibodies that signal the patient's own immune system to attack and clear them. To be most effective, this treatment has to be given as early as possible, before the first signs of cognitive decline. The lab of Patrick Aebischer at EPFL has developed a bioactive capsule containing cells that have been genetically engineered to produce antibodies against Abeta. The capsule itself is based on a design from Aebischer's lab published in 2014. The cells inside the capsule are important. Reference. Mind Control Machine: Human wags rat's tail using mind control interface. Night Owls Smarter: A New Study Suggests That Late-To-Bed-Late-To-Rise Leads To Greater Workplace Success : Healthy Living.
A new study suggests the early riser has only more time for mediocrity. Researchers at the University of Madrid followed nearly 1,000 teenagers and found that night owls bested "morning larks" in qualities linked to general intelligence, such as inductive reasoning, conceptual and analytical thinking. "What hath night to do with sleep? " asked John Milton, the 17th century English poet who worked as a civil servant, among a class of people generally obliged to rise early in the morning. Indeed, while many early risers outperform night owls in school, researchers said the late risers surpass their counterparts later in the workforce. Differences in preset circadian rhythms might explain the 8 percent advantage enjoyed by early risers in school, researchers said. A previous study conducted by the U.S. Jim Horne, a professor of psychophysiology at Loughborough University, commented on the Spanish study.
In comparing the two types, Horne said stark differences in personality emerged. Meditation found to increase brain size. Kris Snibbe/Harvard News Office Sara Lazar (center) talks to research assistant Michael Treadway and technologist Shruthi Chakrapami about the results of experiments showing that meditation can increase brain size. People who meditate grow bigger brains than those who don’t. Researchers at Harvard, Yale, and the Massachusetts Institute of Technology have found the first evidence that meditation can alter the physical structure of our brains.
Brain scans they conducted reveal that experienced meditators boasted increased thickness in parts of the brain that deal with attention and processing sensory input. In one area of gray matter, the thickening turns out to be more pronounced in older than in younger people. “Our data suggest that meditation practice can promote cortical plasticity in adults in areas important for cognitive and emotional processing and well-being,” says Sara Lazar, leader of the study and a psychologist at Harvard Medical School. Controlling random thoughts. 8 Hour Sleep Music Relaxing Music Insomnia Help Sleeping Music Music For Deep Sleep Help ☯649. Berkeley on Biphasic Sleep. If you see a student dozing in the library or a co-worker catching 40 winks in her cubicle, don’t roll your eyes.
New research from the University of California, Berkeley, shows that an hour’s nap can dramatically boost and restore your brain power. Indeed, the findings suggest that a biphasic sleep schedule not only refreshes the mind, but can make you smarter. Students who napped (green column) did markedly better in memorizing tests than their no-nap counterparts. (Courtesy of Matthew Walker) Conversely, the more hours we spend awake, the more sluggish our minds become, according to the findings.
The results support previous data from the same research team that pulling an all-nighter — a common practice at college during midterms and finals — decreases the ability to cram in new facts by nearly 40 percent, due to a shutdown of brain regions during sleep deprivation. In the recent UC Berkeley sleep study, 39 healthy young adults were divided into two groups — nap and no-nap. The Neuroscience of Somatic Attention: a key to unlocking a foundational contemplative practice for educators on Vimeo.
The Creativity Pill - James Hamblin. Health People taking dopamine for Parkinson's disease sometimes begin to generate a lot of artwork. New research differentiates their expressiveness from obsessive or impulsive tendencies. Please consider disabling it for our site, or supporting our work in one of these ways Subscribe Now > Neurologist Rivka Inzelberg recently noticed that her patients with Parkinson’s disease seemed to be authoring more novels than older people tend to author. Looking closer, poems and paintings also seemed to be pouring out of afflicted patients, in a relative sense—specifically those treated with a synthetic dopamine-precursor pill, levodopa (L-DOPA).
So Inzelberg, a professor at Tel Aviv University's Sackler Faculty of Medicine, asked around. Development of uncontrollable artistic urges has been documented in medical case studies. So Inzelberg’s current study tested for symptoms of impulse control disorder, as well as creativity—which it did in a variety of ways. She laughed. Empower Your Brain With Water - Daily Two Cents. Frontiers | Mechanisms of white matter change induced by meditation training | Cognition. Using 100% of Your Brain - Dr. Bruce H. Lipton.
Adverse Cognitive Effects of Medications: Turning Attention to Reversibility. Dangers of Statin Drugs & How They Are Damaging the Brain. This Is Your Brain. This Is Your Brain as a Weapon. 5 Ways Your Brain Is Messing With Your Head. Echolalia. The Toxins That Threaten Our Brains. Yogic meditation reverses NF-κB and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial.