scientists successfully expand bone marrow-derived stem cells in culture | Stowers Institute for Medical Research KANSAS CITY, MO—All stem cells—regardless of their source—share the remarkable capability to replenish themselves by undergoing self-renewal. Yet, so far, efforts to grow and expand scarce hematopoietic (or blood-forming) stem cells in culture for therapeutic applications have been met with limited success. Now, researchers at the Stowers Institute for Medical Research teased apart the molecular mechanisms enabling stem cell renewal in hematopoietic stem cells isolated from mice and successfully applied their insight to expand cultured hematopoietic stem cells a hundredfold. Their findings, which will be published in the Sept. 15, 2011, edition of Genes & Development, demonstrate that self-renewal requires three complementary events: proliferation, active suppression of differentiation and programmed cell death during proliferation.
Professor Hiromitsu Nakauchi, director of the centre for stem cell biology and regenerative medicine at the University of Tokyo in Japan and who led the research, said: "Our ultimate goal is to generate human organs from induced pluripotent stem cells. "The technique, called blastocyst complementation, provides us with a novel approach for organ supply. We have successfully tried it between mice and rats. We are now rather confident in generating functional human organs using this approach." Pigs could grow human organs in stem cell breakthrough
Where can I get more information? For a more detailed discussion of stem cells, see the NIH's Stem Cell Reports. Check the Frequently Asked Questions page for quick answers to specific queries. The navigation table at right can connect you to the information you need. The following websites, which are not part of the NIH Stem Cell Information site, also contain information about stem cells.
Stem cells differ from other kinds of cells in the body. All stem cells—regardless of their source—have three general properties: they are capable of dividing and renewing themselves for long periods; they are unspecialized; and they can give rise to specialized cell types. Stem cells are unspecialized. One of the fundamental properties of a stem cell is that it does not have any tissue-specific structures that allow it to perform specialized functions. For example, a stem cell cannot work with its neighbors to pump blood through the body (like a heart muscle cell), and it cannot carry oxygen molecules through the bloodstream (like a red blood cell). What are the unique properties of all stem cells?
StemGenex | Stem Cell Cosmetic Surgery | Regenerative Medicine A paradigm shift in medicine is taking place as we live and breathe and it is called Regenerative Medicine. At StemGenex®, we are able to offer patients access to cutting-edge adipose stem cell therapies for each of the degenerative diseases seen below. Through our stem cell studies, StemGenex hopes to provide patients with options that may change the course of their lives and benefit them in ways they never imagined possible. The stem cell studies described on this website have been designed by StemGenex® to be overseen by an Institutional Review Board (IRB) in full compliance with all applicable regulations and standards. Those who access this web site should consult their Physician before following any of the suggestions or making any conclusions from the web site. StemGenex® provides information regarding : Stem Cell Research | Stem Cell Doctors | Stem Cell Therapy
Public Stem Cell Companies
The Neural Stem Cell Institute (NSCI) is dedicated to developing regenerative stem cell therapies for various diseases of the central nervous system (CNS): the brain, spinal cord and retina, regardless of the cause of injury. Led by MacArthur “Genius” Award winner Dr. Sally Temple who helped discover and define nervous system stem cells, NSCI is the first independent, non-profit stem cell research institute in the USA. nstemcell.org - Neural Stem Cell Institute
International Society for Stem Cell Research
International Stem Cell Corporation What we do: We help professionals that provide consulting services to C-level Executives (CXOs) who are overwhelmed with the daily responsibilities of corporate communications; are concerned about responsiveness and are worried about meeting their regulatory requirements for investor relations. How we do it: We accomplish this by providing a software and support service, called CXO Suite, that automates contact management between entire team; gives them total control over their website and online marketing campaigns; automates compliance with IR regulations and enables them to get all of their communication products through a single, friendly, low-cost partner.