Top 10 Histamine Containing Foods. Thursday, July 30th, 2009 | histamine Histamine is a biogenic amine that triggers the immune response.
Histamine also acts as a neurotransmitter and has some other physiological functions (such as in the gut). Histamine increases the permeability of small blood vessels so that immune cells and proteins are better able to fight an infection. Histamine is also involved in sleep regulation; too much histamine release in the brain increases wakefulness. Histamine is also thought to make rosacea symptoms worse.