Aging & Anti-aging Search. Anti-Aging. AGING Journal. Human Ageing Genomic Resources. An Introduction to Healthy Life Extension and Engineered Longevity - Fight Aging! Do you want to live a longer life in good health? Simple practices can make some difference, such as exercise or calorie restriction. But over the long haul all that really matters is medical biotechnology: progress towards therapies that can repair and reverse the known root causes of aging.
The sooner these treatments arrive the more lives will be saved, perhaps including yours. So here at Fight Aging! You'll read about healthy life extension, engineered longevity, and the development of rejuvenation biotechnology - but what do these terms mean? Aging is an Enemy, So Fight It! Aging saps our strength and ability to enjoy life, cripples us, and eventually kills us. In future decades researchers will assemble new biotechnologies that can defeat aging, restore the old to health and vigor, and prevent the young from ever suffering the ravages of age. The Limited Means of Today, the Biotechnologies of Tomorrow Three Steps Toward Longevity Step 1: Stop Damaging Your Health Final Thoughts. Exercise increases brain growth factor and receptors, prevents stem cell drop in middle age. Public release date: 18-Nov-2008 [ Print | E-mail Share ] [ Close Window ] Contact: Christine Guilfoycguilfoy@the-aps.org 301-634-7253American Physiological Society BETHESDA, Md.
(Nov. 18, 2008) − A new study confirms that exercise can reverse the age-related decline in the production of neural stem cells in the hippocampus of the mouse brain, and suggests that this happens because exercise restores a brain chemical which promotes the production and maturation of new stem cells. Neural stem cells and progenitor cells differentiate into a variety of mature nerve cells which have different functions, a process called neurogenesis. There is evidence that when fewer new stem or progenitor cells are produced in the hippocampus, it can result in impairment of the learning and memory functions. Rise in corticosterone or fall in nerve growth factor? One hypothesis the researchers investigated is that the age-related decline in neurogenesis is tied to a rise in corticosterone in middle age.
Anti-Aging Breakthroughs. <br/><a href=" US News</a> | <a href=" Business News</a> Copy This is a good time to have some wrinkles on your face. No, really. In the past few years there have been groundbreaking advances in plastic surgery, dermatology and the ever-expanding anti-aging cosmetic industry. Back in the day, your mom probably used a wrinkle cream on her face that promised to "hydrate" her skin and reduce fine lines. If you have some fine lines, a few wrinkles but you're not yet ready for the "f" word (facelift), an anti-aging cream might be right for you. "We are using nano liposome technology with a capsule so small that is gets absorbed through the hair follicles and releases the active ingredient into your skin," said John Kressaty, head chemist at 3Lab, Inc. "Nano liposome is a very small particle that is able to pass through the skin to deliver vital nutrients. "HGH is a hot news topic and our "h" Serum is totally efficacious.
Chinese Herbal Medicine: The Longevity Factor and on Living to 197 Years. (NaturalNews) With all of the marvelous inner-workings of the herbal TCM system (traditional Chinese medicine system) and its powerful and complex systematic energy formulas for healing practically anything, it is still the longevity factors of a few single tonic herbs that amaze me the most. Of about 9,000 TCM herbs (officially used in TCM and fully understood in their energy factors) there are about 100 that can truly contribute to a long healthy life. (These are in the "Superior Tonic Herb" classification.) About 40 of these herbs are quite remarkable in there abilities to prolong life with very little signs of ageing.
If I were to narrow it down a bit further, at least on a personal level, I would say the most important herbs for longevity would come down to about fifteen with He Shou Wu (Polygonum multiflorum) being the most important. There is simply not enough room here to go into all these but below are links with photos and an in-depth look at each of these herbs. Scientists stop the ageing process › News in Science (ABC Science) News in Science Monday, 11 August 2008 ABC/AFP Scientists have stopped the ageing process in an entire organ for the first time, a study released today says. Published in today's online edition of Nature Medicine, researchers at the Albert Einstein College of Medicine at Yeshiva University in New York City also say the older organs function as well as they did when the host animal was younger. The researchers, led by Associate Professor Ana Maria Cuervo, blocked the ageing process in mice livers by stopping the build-up of harmful proteins inside the organ's cells.
As people age their cells become less efficient at getting rid of damaged protein resulting in a build-up of toxic material that is especially pronounced in Alzheimer's, Parkinson's and other neurodegenerative disorders. The researchers say the findings suggest that therapies for boosting protein clearance might help stave off some of the declines in function that accompanies old age. 'Misbehaving proteins' Settles debate. Anti-Aging Publications. The scientific legitimacy of the term "anti-aging" is sometimes questioned because it is often associated with advertisements like these: Therefore it is very important to see this list: List of Legitimate Studies,Published in Reputable Scientific Journalsby Established Researchers,Which Use the Term "Anti-Aging" to Describe the Postponement of Chronic Diseases, Frailty and Death The terms like 'anti-aging' in the titles of the publications are highlighted in CAPITAL letters: Armstrong SM, Redman JR.
Recently, it has been reported that melatonin administration extends the lifespan of mice, a finding which supports previous research on the effects of pinealectomy and pineal extract administration. Bergamini E, Cavallini G, Cecchi L, Donati A, Dolfi C, Gori Z, Innocenti B, Maccheroni M, Marino M, Masini M, Paradiso C, Pollera M, Trentalance A.
No abstract available at this time Boldyrev AA, Gallant SC, Sukhich GT. Cavallini G, Donati A, Gori Z, Pollera M, Bergamini E. De Grey AD. Hipkiss AR. Sleep less, live longer? Embargoed by Archives of General Psychiatry for 4 pm (EST) Feb. 14, 2002 Sleep less, live longer? Increased Death Rate Associated With Sleeping 8 Hours or More Although it’s a common belief that 8 hours of sleep is required for optimal health, a six-year study of more than one million adults ages 30 to 102 has shown that people who get only 6 to 7 hours a night have a lower death rate. Individuals who sleep 8 hours or more, or less than 4 hours a night, were shown to have a significantly increased death rate compared to those who averaged 6 to 7 hours.
Researchers from the University of California, San Diego (UCSD) School of Medicine and the American Cancer Society collaborated on the study, which appeared in the February 15, 2002 issue of the Archives of General Psychiatry, a journal of the American Medical Association. Although the data indicated the highest mortality rates with long-duration sleep, the study could not explain the causes or reasons for this association.
Photos of Dr. Meat and two neutrons -- the key to a longer life. Indulging in an isotope-enhanced steak or chicken fillet every now and again could add as much as 10 years to your life. Scientists have shown for the first time that food enriched with natural isotopes builds bodily components that are more resistant to the processes of ageing. The concept has been demonstrated in worms and researchers hope that the same concept can help extend human life and reduce the risk of cancer and other diseases of ageing, reports Marina Murphy in Chemistry & Industry, the magazine of the SCI.
A team led by Mikhail Shchepinov, formerly of Oxford University, fed nematode worms nutrients reinforced with natural isotopes (naturally occurring atomic variations of elements). In initial experiments, worms' life spans were extended by 10%, which, with humans expected to routinely coast close to the centenary, could add a further 10 years to human life. Ageing experts are impressed with the isotopic approach. Source: Society of Chemical Industry. Heavy Water Could Extend Lifespan in Humans by Preventing Free Radical Damage by Mike Adams the Health Ranger. Russian biochemist Mikhail Shchepinov may be on to something big.
He's been developing heavy water technology and testing it on various animals to see how the substance might reduce free radical damage and extend lifespan. Although results are preliminary, one test with fruit flies showed an increased lifespan of 30 percent. Heavy water is just like H2O except that the hydrogen atoms are replaced with deuterium, making D2O. Because heavy isotopes have stronger chemical bonds, they resist oxidation far better than the lighter hydrogen molecules. As a result, they act sort of like "oxidation body armor" for cells. And because aging is caused in part by the free radical breakdown of cellular function, heavy water should extend lifespan when consumed by humans or animals. Of course, aging involves a lot more than just free radical damage. Every time you take a pharmaceutical or eat junk food, you are accelerating your aging. Related Feature Articles: Supercentenarian Research Foundation Main Page.
Brain Growth Receptors Control Lifespan. Citation: Robinson R (2008) Brain Growth Receptors Control Lifespan. PLoS Biol 6(10): e274. Published: October 28, 2008 Copyright: © 2008 Richard Robinson. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. When resources are short, growing organisms face an existential choice: should you ignore the shortage and hope for better times soon, or scale back and live within your limited means? And if you do scale back, will there be any payoff later in life? In mammals, two principal hormones—growth hormone (GH) and insulin-like growth factor 1 (IGF-1)—promote growth.
The authors were led to the brain by the hierarchy of the endocrine system itself. Mean lifespan was also increased in the knockout mice, by about 10%. SENS Foundation | Advancing Rejuvenation Biotechnologies. Review: The People's Guide to Health, Happiness and Longevity Reveals Life Enhancement Secrets of 12 Top Experts. (NaturalNews) For the last several months, I've been collaborating with renowned author, entrepreneur and content creator Craig Pepin-Donat on a unique, high-density content program that's just been announced this week. It's called The People's Guide to Health, Happiness and Longevity, and it features twelve audio CDs of edited interviews with featured health and fitness experts, twelve more bonus reports, videos and content items, an ebook and a hardcover copy of The Big Fat Health and Fitness Lie.
Together, it's an extremely content-rich collection of some of the best information that's yet been offered to the public on health, fitness and life enhancement. In this article, I review this content course and share why I think this is the top collection of immediately useful health information available today, featuring an impressive lineup of health gurus and experienced teachers. Of course, I'm biased in this review.
Dr. Dr. Other experts included in the course are: #51 - Evolution of Aging - What are the prominent theories of how we age? | Sage Crossroads. Research. Welcome to the research area of the Shay / Wright Laboratory. Information about Dr. Shay and Dr. Wright's research into telomeres and telomerase is contained here. For a more general overview of what telomeres and telomerase are, go to the Basic Introduction to Telomeres and Telomerase area of the site. Specific questions (and their answers) can be found in the FAQ. Overview of Telomeres / Telomerase Aging and Telomeres Cancer and Telomeres Shay/Wright Laboratory Methods Overview of Telomeres / Telomerase Telomeres are composed of repetitive DNA sequences at the end of linear chromosomes.
Cellular senescence may have evolved, in part, to protect long-lived organisms, such as humans, against the early development of cancer. In addition to the accumulation of several mutations in oncogenes and tumor suppressor genes, almost all cancer cells are immortal and, thus, have overcome the normal cellular signals that prevent continued division. Aging and Telomeres Cancer and Telomeres References. Herbal Rhodiola Extract Found to Increase Lifespan. Pill to Beat Aging | Microbiology | Discoveries and Breakthroughs Inside Science.
Reported March 2009 CHARLOTTESVILLE, Va. (Ivanhoe Newswire) -- As we age, it's natural for our bodies to weaken and become frail, but the natural progression can limit physical activities in the elderly. A new drug is being touted as an anti-frailty pill. Jack Gwaltney keeps active training his dog Ajax, but admits aging has taken a toll on his body. "I am fortunate that I do almost everything that I could do, but I don't do it as well," Gwaltney told Ivanhoe. As we get older, we lose muscle mass, mainly in the arms and legs. "By the time you've reached the age of 70, the average loss of muscle is about 6 kilograms, which is over 12 pounds," Michael Thorner, M.D., an endocrinologist at the University of Virginia Health System in Charlottesville, Va., told Ivanhoe. A new drug called MK-677 has been shown to increase 20 percent of the lost muscle mass that occurs between mid-puberty and age 70 -- a significant boost in muscle.
That's something Gwaltney hopes for himself lasts a long time. Long Life Family Study. Certain personality traits may be important to healthy aging. The work was conducted in collaboration with scientists from the National Institute on Aging. These findings currently appear on-line in the Journal of the American Geriatrics Society. Previous research on siblings and offspring of centenarians have documented that exceptional longevity runs strongly in families. Studies of the offspring of centenarians showed that their mortality is 120 percent lower than other members of their birth cohort and that they also have markedly lower prevalence rates and delayed onsets of cardiovascular disease, hypertension, and diabetes mellitus.
Because personality traits have been shown to have substantial heritable components, the researchers hypothesized that certain personality features may be important to the healthy aging observed in the offspring of centenarians. Both the male and female offspring of centenarians scored in the low range of published norms for neuroticism and in the high range for extraversion.
International Antiaging Systems Authors. List of living supercentenarians. This is a list of living supercentenarians (people who have attained the age of at least 110 years). To be verified, a supercentenarian must have their age validated by an international body that specifically deals in longevity research such as the Gerontology Research Group (GRG).[1] Verification usually requires that at least three documents contain the same date of birth. Pending cases are those that have presented sufficient documentation to a verifying body in the process of validating (or otherwise) those documents. Unverified cases are those where a person is reported to have been born more than 110 years ago in a reliable source, but sufficient documentation has not yet been produced for verification. This article lists only those people confirmed alive within the past year. The list includes 71 verified supercentenarians, the oldest of whom is Japanese woman Misao Okawa, aged 7002116000000000000116 years, 700140000000000000040 days.
Verified living supercentenarians[edit] What Does Life-Extending Drug Rapamycin Mean for Humans? Fitness Level, Not Body Fat, May Be Stronger Predictor Of Longevity For Older Adults. Longevity & Life Expectancy Calculator – Eons.